Preimplantation Genetic Diagnosis (PGD) - Glossary

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Glossary


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Preimplantation Genetic Diagnosis (PGD)	The procedure used to detect genetic or chromosomal abnormalities on embryos created during an IVF cycle. This is a delicately precise micro-manipulative procedure, in which embryologists remove either necessary DNA from the egg shortly after fertilization (polar body biopsy) or a single cell from a three-day old embryo (embryo biopsy). Molecular biologists examine the polar body or embryo biopsy for specific genetic anomalies. This is appropriate if a woman is 35 years of age or older or if the couple carries a genetic abnormality which they do not want to risk transmitting to the fetus.
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